The current Ebola epidemic in the Democratic Republic of Congo – with 426 total cases, including 245 deaths – is now the second largest and second deadliest in history, according to Thursday’s report from the nation’s Ministry of Health.
A 2000-01 outbreak in Uganda included 425 cases and caused 224 deaths, according to the World Health Organization.
On average, Ebola – which causes fever, severe headache and in some cases hemorrhaging – kills about half of those infected, but case fatality rates in individual outbreaks have varied.
The latest outbreak in Congo, which began in August, has a case fatality rate of 57%. Of the total cases, 379 have been confirmed, and 47 are probable, according to the ministry.
North Kivu province, which includes the cities Beni, Kalunguta, and Mabalako, remains the epicenter of the outbreak, though cases have been reported in neighboring Ituri province, according to WHO. The two provinces are among the most populated in the nation and border Uganda, Rwanda and South Sudan.
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