Welsing was born March 18, 1935, in Chicago. Both her father and grandfather were medical doctors, and her mother was a teacher. She received her bachelor’s degree from Antioch College, and her M.D. from the Howard University College of Medicine. In 1974 Welsing became famous for her paper “The Cress Theory of Color-Confrontation,” which she published while an assistant professor of pediatrics at Howard’s medical school.
Welsing is perhaps best known for her 1991 book, The Isis Papers, which reportedly came about after 20 years of research and analysis from her private practice. It is considered required reading for those interested in the psychological origins and manifestations of white supremacy.